Human papillomavirus (HPV)–associated oropharyngeal cancer is on the rise, but at Memorial Sloan Kettering Cancer Center, we have updated our standard of care to substantially reduce the radiation dose to elective regions.

In our paper, published recently in the journal Practical Radiation Oncology, we summarize our current standard dose prescriptions and explain the rationale for our choices. Our recommendations are based on the American Joint Committee on Cancer Seventh Edition tumor-node-metastasis staging system. Note that these recommendations apply only to patients who receive concurrent platinum-based chemotherapy and who test positive in both p16 immunohistochemistry and HPV RNA in situ hybridization tests.

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In 2019, MSK clinical researchers made several major discoveries that will improve the treatment of cancer and guide the development of new therapies. Many of these studies were made possible by large and small philanthropic donations, which allow researchers to pursue innovative ideas and take the risks necessary for breakthrough discoveries.

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I Had My Stomach Removed and Then Did an Ironman: Dylan’s Story

Dylan, a young father of three, had a genetic mutation that put him at a high risk for stomach cancer. He traveled from South Carolina to MSK for preventive surgery. Today, he is back to doing the things he loves, like competing in triathlons.

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